It gives them their characteristic deep voices, large muscles, and facial and body hair, distinguishing them from women. It’s not all in print. would if be more beneficial to inject 50mg of test twice a week? I need an answer regarding getting testoroene after having your Prostate removed. She started trying about a drop a day to see if her libido would improve, and it did, dramatically, and also her moods and patience. I opted for the gel. He referred me to an IDIOT endocrinologist, and he which tested me again and got a level of 187. Society help boy to become little girls because they think “they will feel better”. This is an area that has tremendous research potential in the coming years.*. However, in many other countries, the opposite is true. If you are not feeling good on TRT then you should have your E2 checked because it is probably over 30 which will counteract the effects of your free T. I’m a 70 y.o. And no wonder so many endocrinologists hate HRT: their patients hate their lame protocol. You will eventually damage your liver no matter what their advertising tells you. I switched to four pumps per day, and I felt immediate effects. The results were very revealing: What this study clearly showed is that testosterone levels are actually raised a little over baseline after a week, which explains why a weekly protocol is so often successful. I was age 55 with T level at150 so the va doctor started me out on bi weekly 200mg injections.Needless to say it really made me fell young again. Although this improves within the first few days, you may not notice the effects for 3-12 months. Before I was tired and lacked the mental clarity I now feel. Cernos depot is an equivalent to Nebido and holds testosterone undecanoate. 250iu of HCG: Mon&Wed only. PMID: 10362098. You don’t need to feel OR act like you’re 18 years old again, this is life. Interesting when I spoke to some friends about this and they have now gone and got tested and have come back with low Testosterone and the doc never picked up on it. I am over weight with a fat belly. My last blood test showed normal except my estrogen was right at the recommended max but still with in limits. I started T therapy several years ago. It’s not just a pep pill to give you more energy and a better boner. I am 27 yrs and on Cernos depot( 1000 mg ) shot since 3 years after I was advised by an Andrologist as I was uncomfortable with other injectable esters due to its roller-coaster behaviour. Im self-employed….. My energy levels are the only thing that makes me money to provide!!! I am thinking of stopping the HRT because i felt it is worsening the illness. He does a most wonderful job of balancing quality of life with safety aspects. I do not know what to think but am trying to find all the information I can on the subject as I am quite nervous. I’m 56 and 5 years ago dropped to 270 with all the side effects listed for low test. The goal is to restore the circadian rhythm which impacts hormone productiion. I know this is vague info. I have lost energy, sexuality, and mood. Anyone who reads your comment will waste at least 20 seconds of their life. If men’s brain, muscles, and bones are being affected daily due to low testosterone, and it is what makes men, men, why aren’t we doing more about this serious health problem? Excellent article on men’s health! It’s is universally accepted and part of a woman’s life without a doubt. Levels got down to 78 at one point. AC, I just ran across the thread… definitely start the injections. In the first week I feel a lot stronger, voice deepens etc but these benefits quickly diminish after about 5-7 days. My biggest complaint is feeling tired. Jeremy, I hope it helped and that you are feeling better. What about hair loss in administering hormone replacement therapy with AndroGel? My oncologist is also a graduate of Harvard like the doc that wrote this article. Now I have a low T blood test along with symptoms of Low T. I am familiar with the concept of testosterone replacement therapy “feeding the fire.” But I also am aware of numerous studies that say that there is no danger from testosterone therapy to one that had/has prostate cancer. last test was 312 ng/dl. Over-the-counter hearing aids: Are they ready yet? But last year (in september) I started using vitamine D (10 000 IU) and K2 (180 mcg), combined with magnesium (200 mg malate) and zinc (25 mg malate and piccolinate) every night, and since then I no longer have low testo in the winter, and is feeling like I do in the summer and have normal testo levels. Fears about statin side effects: Often unfounded? Not great but much better so I will continue. Thanks. The “drive” is either there or not, serving to motivate a guy to even take the pill to begin with. If not…..how many days ll be effective per dose?? Our doctors put our patients health above all else especially above the all mighty dollar. I just started trt. Especially the oral version. Any recommendations. Nevertheless, the risk exists, so we want to be careful about giving testosterone to men who already have a high hematocrit, such as those with chronic obstructive pulmonary disease, or those who have a red-blood-cell disorder. I would be under the doctor’s care of course with PSA and Testosterone levels monitored regularly. The fact your a doctor gives zero confidence that you have any knowledge in HRT, in fact I believe it where you wonderful doctors that started the larger opioid epedemic the world has ever seen. My question is this: if I take testoroene will my PSA levels go up and will the cancer come back? This is in an infection in a diverticula that forms in your intestines. Drs goal is to get me just over that line. In general, the dosage is 50–400 mg injected into your child’s muscle every 2–4 weeks. The energy was phenomenal and in demand. Correction on the HCG, it is 50IU not mcg taken twice weekly. They prescribe 50 mgs a week. There have been a number of smaller studies on men receiving testosterone-replacement therapy, and if you look at the results cumulatively, the rate of prostate cancer in these men was about 1% per year. Dustin, I was reading through the comments and thought I’d check in to see how long you stuck with it and how it worked. Depending on the formulation, treatment can cause skin irritation, breast enlargement and tenderness, sleep apnea, acne, reduced sperm count, increased red blood cell count, and other side effects. i feel like everything is fading. So pull up the above study and show your doctor just what is going on. We did bloodwork and My testosterone levels were lower than a woman! I found that everyone out there has their own idea of what is best yet, here is my issue. PMID: 11200304. My last T level was at 365 . There is a protocol however to get back to your normal production much quicker should you choose to quit therapy. How long does it take for them to work? So she went off it. It’s better now, but my doctor and I want to get that down to around 500, so I’m going to 20-21 days and see what happens. Can I get testorone in a pharmacy or a health store? Barry I’d like to know more about what you mean about oesttogen for xxy. It can also increase the oiliness of the skin, so that some men get acne or pimples, but that’s quite uncommon, as are sleep apnea and gynecomastia (breast enlargement). Moffat SD, Zonderman AB, Metter EJ, et al. What do i do people??? What forms of testosterone-replacement therapy are available? Originally published March 2009; last reviewed February 18, 2011. My Dr. did PSA every 6 months and my PSA over almost 2 years went from 1.16 to 1.67, still pretty low for 56YOA He wanted to do a biopsy and he found 1 out of 12 cores 60%, GS3X3. My preference is to start men on testosterone, for a couple of reasons. Looking for help in regards to my situation. . I am 35 and had the non sexual symptoms for awhile now( weight gain/muscle loss, extreme fatigue, lack of clarity/concentration) I got my testosterone levels checked last week and it was 35.4 ng. I feel great for the full 2 weeks… This has been pure hell. it is a resource for men like us that give answers, science and dialogue which addresses our questions. I have been living in a hot climate or aircon for the last 20 years. I have administered 10 X the recommended dose with no bad side effects. Granted, I wasn’t getting spontaneous erections like when I was a teenager and into my late 20’s, but that was a good thing as getting an erection whenever and having no way to relieve it can get annoying. I started doing prostate biopsies before putting men on testosterone therapy because the fear had always been that a hidden cancer might grow due to increased testosterone. Just something to think about people before you take some quacks advice. I am almost double that now and my estrogen is high as I explained above. Is this an “ALL IN” therapy? I intend to get back to Androgel. Pretreatment Total Testosterone Level Predicts Pathological Stage in Patient with Localized Prostate Cancer Treated with Radical Prostatectomy. Disappointed. . He speaks with the intent that nothing he says matters to him regardless of bluntness or disrespect. The down side was Insurance didn’t cover it and I had to pay $50 a month vs free shots from the doctors office or $10 for the so-called gels. The first week after the injection. How long will my hip or knee replacement last? If you’re suffering with withdrwal, here’s one of the few articles online that will be informative. Apparently, my body reacted and took to it very quickly and easily, but the T level was now TOO high. Notes: Premenopausal women produce about 230 ± 70 μg testosterone per day (6.4 ± 2.0 mg testosterone per 4 weeks), with a range of 130 to 330 μg per day (3.6–9.2 mg per 4 weeks). Longitudinal Assessment of Serum Free Testosterone Concentration Predicts Memory Performance and Cognitive Status in Elderly Men. Still, my doctor and reading indicate that fat has an effect on T potentially lowering the overall level that my T would be if I lost a good amount of that fat. I see this is an older thread, but still very appropriate. Preliminary research has shown that clomiphene citrate (Clomid), a drug generally prescribed to stimulate ovulation in women struggling with infertility, can foster the production of natural testosterone, termed endogenous testosterone, in men. My body shape is not the typical huge “beer belly” gut that is hard and dangerous, rather, I am fat all over proportionally, but still considered obese. You sweat or you have to take a shower in the mornings and the gel sucked to apply. I guess my question is if I quit the program, will my body return to its normal, or will it be worse. After the hospital I went see my gastro who was a board member of a large anti aging group of doctors. I would say that my testicles are about half the size they were just 4 months ago. .by way the past without andro gel…little too no energy..weight gain of 40 lbs..especially around the belly..thank you for your time and reply, I started TRT therapy this week and this site has gave me some great insight thank you. So what about someone like me who is 35 and produces almost none? Most of the time, … I thought that scientific inquiry suppose to go where the evidence leads. and the weekly visits for injections. I still find it very hard to wake up, get motivated etc etc. Enough already!!!! Doc put me on cymbalta (slept even more than 14hrs daily) then on Wellbutrin. Am looking for comparison of gels to cream. I had a reoccurrence of my prostate cancer in 2013 and underwent radiation. Type A personality, hyper active all my life. When most doctors learned about testosterone in medical school, they learned about total testosterone, or all the testosterone in the body. It worked great but having kids around I was worried about it affecting them so we switched to in ejections taken every 2 weeks of cypionate 200mg and my wife helps me with that at home and I never stray from the regime . I’m 30 year old male how can I increase my sexdrive with out testosteron ijection thanks. Testosterone: Its Role in the Development of Prostate Cancer and Potential Risks from Use as Hormone Replacement Therapy. Don’t settle. physician, on 100 mg T IM weekly for 7 years, levels stay at 1000, check T, Hemoglobin and estradiol levels once yearly. Most guidelines still say it’s important to do the test in the morning, but for men 40 and above, it probably doesn’t matter much, as long as they get their blood drawn before 5 or 6 p.m. Since my last 3 shots, I have been feeling a loss of focus/strength after 5th week from taking each shot. Has anyone used this much to get there levels up? I was reading an article written by expert Lee Myer over on Peak Testosterone about his first … That may be what brought the patient into the office originally, but then he comes back saying how much better he feels in general, how much more energetic and motivated he is, how his drives on the golf course seem to be going farther, and how his mood is better. I found out the hard way. I was wondering if tongkat and myomin would be helpful with lowering estrogen and increasing testosterone. Are there studies (risks) to long-term TRT? Our doctors (PCP, Endo’s, Uro’s) are far behind the curve on this subject even though hormones have been experimented with on farm animals and humans (body builders and olympians) for over 50 years. I am planning to take TRT with Testosterone mix called SUSTANON 250 mg per week and HCG 5000 IUs twice a month. Everything is normal so far. We reside in Richmond, VA. Doc told me to inject my weekly Cypionate into sub fat for longer absorption, with reference you shared this info him with him. After around the 3 injection I had a blood test and my T level was OVER 800, something like 832. I was able to pursue my endeavors with the energy provided, I was able to think about running and exercising and then put that thought into action. Testosterone undecanoate (restricted availability): 750 mg IM initial dose, repeat after 4 weeks, and then q10wk thereafter. Also have less sensitivity during sex and it takes longer to orgasm. I saw the ads on TV and my GP wrote a script. My hubby has been using 1.62 androgel Now 4 pumps a day) for 3 years. Excellent article. Only thing is my PSA is slightly high which my doc wants to check out as a precaution, don’t believe it has anything to do with testosterone therapy. Then he gave me the injection of 200mg test . Then after 7 days or so all gone bad nerves started back up . We call it androgen deprivation or androgen-suppressive therapy.) After 90 days, it seemed like the Andro Gel kind of stopped having it’s effect. with this different doc then I use to have . Personally, if all webmasters and bloggers made good content as you did, In its 2004 report, the Institute of Medicine (IOM) committee studying the need for clinical trials of testosterone-replacement therapy noted that only 31 placebo-controlled studies had been done in older men, with the largest one enrolling just 108 participants. Stopped taking it and now use Primo Testostin Depot (test enanthate – 1 x 250mg shot every 2 weeks). No real change in libido, have always been a horny little bugger. Saw urologist last week. When I’m not going to the gym, or traveling, I cut down to 2 pumps, or take a break for a few days. I am not sure what to take. My Cardiac health is the best is has been in 10 years. Every 4-5 months, very happy with results to date. An Aromatase Inhibitor (AI) or anti estrogen medication (Clomiphene, Tamoxifen) is needed to stop the estrogen from getting out of control. The more of these symptoms there are, the more likely it is that a man has low testosterone. I have such DRIVE and AMBITION I can’t believe it I look and act 30 years younger. I am 37 yoa, and hade chronic low T for years. I was hospitalized for 4 days and it was horrible. No one told me I would be hooked for life, either. My husband is on testosterone injections and Anastrozole that stops the testosterone from turning into estrogen. So she wanted to start me on Clomid. I read all these studies, hear in the news, and see all these dumb lawsuit commercials about testosterone causing cardiovascular events, blood clots and many other things. Our bodies have a lot more hormones to balance than just testosterone and estradiol and the crash can be a little rough if you have to stop. So, I’m no longer worried that giving testosterone to men will make their hidden cancer grow, because I’m convinced that it doesn’t happen. I started testosterone therapy in January 25th 2014. Journal of Clinical Oncology 2000;18:847–53. Doctors can be as dangerous as they are helpful; as we have seen quite clearly with the opioid epidemic being experienced in this country, as I mentioned above. He is the best. I started a Testosterone cream that is compounded over a week ago 100mg daily. Clinical Review 171: The Rationale, Efficacy and Safety of Androgen Therapy in Older Men: Future Research and Current Practice Recommendations. Given the choice between giving up my prostate or giving up my T? He has developed particular expertise in treating low testosterone levels. And the main question is,only the aged persons have to take r even young person’s also can take?? What’s your thinking on performing a prostate biopsy before prescribing testosterone therapy? In my mind I’m 37 so I think it’s all normal. The really bad thing is that I’m traveling for work and cannot get into my doctor’s office. Like 110. On top of this Estrogen can bind to your androgen receptors causing Testosterone to float around with no where to go. And we had a large enough group to look at the impact of testosterone on cancer risk. The prostate has shrunk to a much smaller size and the PSA has been undetectable for 20 years. After about a month of feeling 30again, she started noticing lite facial hair developing, decreased breast size, and return of all previous symptoms. PMID: 15126525. Albumin 4.1. There’s no concrete evidence, a direct link so to speak, that testosterone therapy causes prostate cancer. Men may experience other symptoms, such as more difficulty achieving an orgasm, less-intense orgasms, a smaller amount of fluid from ejaculation, and a feeling of numbness in the penis when they see or experience something that would normally be arousing. I tried patches, but they were too much of a hassle for me especially when you start to work out more. This is a particularly relevant topic, because an every-two-week protocol is still practiced by most endocrinologists around the globe. Is total testosterone the right thing to be measuring? My blood has always been quick to coagulate. Yes, 10 times the recommended dose. mostly just more vitality and a better outlook on life. By activating your account, you will create a login and password. When he takes his weekly shots, he experiences rapid mood changes and is quick to anger. If you think you may have a medical emergency, call your healthcare provider or 911 immediately. Also had 2 kids in last 5 years,(second marriage) , and at times have a hard time tolerating the stresses due to lack of energy to cope with the increased emotional load. long story short, I’ve had nothing but good things from testosterone therapy. Mainly liver toxicity that I noticed and just the general idea of not really knowing what was in it. Been unable to work for 2 years. PMID: 11337297. I’ve forgot to mention that I’ve been on this regiment for at least 3 years or so and do have my blood tested twice a year. Yes he was great with laments terms, made it real easy to understand n absorb…. WTH. Is it imperative to take anastrozole with TRT? Journal of Clinical Endocrinology and Metabolism 2002;87:5001–7. This is extremely important to keep this in mind. As of January 2011, it was still awaiting FDA approval.]. TRT sent my drive into negative overdrive: ambition, cunning, entrepreneurial risk, physcal and psychological risks: drugs,you name it. Also had high prolactin. Testosterone levels that are too high or too low may cause a range of potential … Men produce testosterone measured in the order of ng/ml or ng/dl. ..i don’t know is true or not??? I don’t know if using a more “natural” testosterone will give better results, but a friend of mine gets his T from a formulay pharmacy that creates, blends, or mixes a different type of testosterone that is promoted to be more natural to the human body. Also get outside in the sun in the AM. My only concern is my medical consultant. i have a free T of 0.1 ng/L and bio available of 3.6 ng/dL. It’s not like diabetes, where if your fasting glucose is above a certain level, they’ll say, “Okay, you’ve got it.” With testosterone, that break point is not quite as clear. I had a RP in 1995. My doctor told me to discontinue the injections pending another biopsy when I’m 65 in June. Told him the problems I was having , which included a horrible down mood , no energy . I’m on shots and am trying to taper the methadone now. I was lucky it happened after 50 years of memories ’cause I missd and have problems recalling the last seven years that I was on TRT (5 pumps a day of 1.25mgs). My level was 429 the first time and the second time 356. But after reading your article I must conclude that the odds are not so bad and that a little higher testosterone can be a good thing. Law suits are out about T and blood clots. Not easy but worth every second. Recently I went to check my blood for low T and was shocked but not surprised at the level (125). Has anybody been following the profgress of Lipocine and their NDA submission for twice a day oral TRT? However, it failed to key in on the psychological effects which cause noted behavioral changes. It had a click dispenser that looked like a deoderant that would pre-measure the dosage and I could rub it on my arms and shoulders or on my neck, really anywhere not covered in hair but the thinner the skin the better. Thanks. Just need to get my T level on track with a doctor that will listen to how his patient is feeling . What I also noticed is that he is now acting more dominant and agressive in his behavior. i am 20 y.o male with 200 ng/dl testosterone. Am 82 year old retired doc. I am in great shape and work out all the time. Problem solved. I just don’t like the way it makes me feel. Gels are a weak joke. I have low cortisol and my doctor decided to check testosterone. On testosterone replacement for the past 3/4 years using an injection (self administered) every 10 to 15 days intervals of 200mg/mL at 0.8ML even though prescribed once a week. But unlike exogenous testosterone, clomiphene citrate preserves — and possibly enhances — sperm production. One is a blood test and the other is by characteristic symptoms and signs, and the correlation between those two methods is far from perfect. Test enanthate half life is 5,25 days (1/2 * ester chain length) this means 200 mg will be almost 0 after 2 weeks and nowhere near to be found after 4. a healthy adult at 20 produces an amount of 200 mg per week more or less. Similar to its effects on energy, experts don't … After close to 10 years of twice-weekly injections of 20 units of testosterone cypionate my PSA gradually increased from 4.4 to more than 16. Feel so down and out. So I was prescribed 2.5g 1% androgel, after two weeks I did not feel a difference , on the box it says that the recommended dose is 5g 1% , so my doctor prescribed the 5g 1 % , its now a week since I started the 5 g ( all together three weeks since I started androgel ) & now I feel great, my mood and energy level is way better, I never had an issue with my libdo , so no difference there. Still an unfortunate cost for a medical reason that the insurance companies don’t approve. Generally, if you are an ass, or high strung, this will amplify it. It came back at 5! WHY? Vote. So I went on to check back often and got the same reply , were out of supply . I turn up the heat and T , my body turns up the aircon which suppresses the T. I can’t find any discussion on correlation between temperature/climate and T anywhere but given that we all live in climate controlled environments now seems worthy of some study. I am now almost 56. But recently I purchased from Briland Brands on amazon PaleoTest. The general comments on this page apply to BOTH enanthate and cypionate. I’ll stay on it until and if negative signs/symptoms arise. Last time fasting it was 53 but was 50 a few days later when checked at 2:00pm not fasting. It came back at 23. Not a bad thing but sometimes it takes way too long. The disadvantage is that a man needs to come in every few weeks to get a shot. . At the end of the study period, the researchers see who developed prostate cancer and who didn’t. It’s being found too often that hypogonadism is pared with another abnormality of the endocrine system called Hypothyroidism which causes intense fatigue and even alzheimer like cognitive disruption. Testosterone Enanthate is a long ester and has a half-life of 4.5 days. I actually thought oh well this is what happens when you get older.
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